Journal: Sensors (Basel, Switzerland)
Article Title: Targeted FT-NIR and SERS Detection of Breast Cancer HER-II Biomarkers in Blood Serum Using PCB-Based Plasmonic Active Nanostructured Thin Film Label-Free Immunosensor Immobilized with Directional GNU-Conjugated Antibody
doi: 10.3390/s24165378
Figure Lengend Snippet: PCA plots of ( a ) FT-NIR and ( b ) SERS after interaction with HER-II in BCS. The groups within each sample are easily distinguished by PCA-LDA. The group members are closer to each other than in the case of FT-NIR, i.e., more statistically meaningful; however, both groups are clearly distinguishable.
Article Snippet: The absorbance was measured using a UV-vis spectrometer (Jenway 7205-Cole-Parmer, Quebec, QC, Canada) covering a spectral range from 198 to 800 nm. a illustrates the FT-NIR setup in reflectance mode, where the PCB was analyzed using an FT-NIR Nano Quest spectrometer (NanoQuest 2.5, Ocean Insight (Gamble Technology), Mississauga, ON, Canada).
Techniques: